Molecular Formula | C20H34BCl |
Molar Mass | 320.75 |
Density | 0.954g/mLat 25°C |
Melting Point | 52-56°C(lit.) |
Boling Point | 66-69°C |
Flash Point | 82°F |
Vapor Presure | 2.63E-06mmHg at 25°C |
Appearance | clear liquid |
Color | Colorless to Almost colorless |
BRN | 5937756 |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | -51 ° (C=neat) |
Use | (-)-diisopone chloroborane is a kind of chiral reduction reagent commonly used in the drug production process, mainly used to put the aldehyde group in the drug molecule, ketone groups are directly reduced to alcohols with chirality. It is widely used, especially in the production of some high value-added drugs at home and abroad. |
Risk Codes | R34 - Causes burns R20/22 - Harmful by inhalation and if swallowed. R12 - Extremely Flammable R10 - Flammable R67 - Vapors may cause drowsiness and dizziness R65 - Harmful: May cause lung damage if swallowed R62 - Possible risk of impaired fertility R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R48/20 - R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R11 - Highly Flammable R37 - Irritating to the respiratory system |
Safety Description | S9 - Keep container in a well-ventilated place. S16 - Keep away from sources of ignition. S29 - Do not empty into drains. S33 - Take precautionary measures against static discharges. S36/37 - Wear suitable protective clothing and gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | UN 3261 8/PG 2 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29319090 |
Hazard Class | 3/8 |
Packing Group | II |
purpose | ( )-and (-)-DIP-chloride can be used for the asymmetric reduction of prochiral ketones and the preparation of β-amino alcohols. |